This session will review the basic science literature as it pertains to injury, healing, and adaptation of tissues injured in common musculoskeletal conditions. The speakers will address the rate of repair and the extent of regeneration for bone, cartilage, muscles, tendons, ligaments, and nerves. The impact on the rate of healing and the regenerative capacity of these various body tissues produced by the inflammatory response, systemic health conditions such as diabetes or metabolic syndrome, as well as commonly used medications like NSAIDs will be discussed. Patient case studies will be presented to illustrate how this knowledge base guides clinicians in their decision-making process.

Course Code:


Completion Instructions

  • Complete the posttest with a score of 70% or higher, and
  • Complete the Learning Center surveys to earn your CEUs.
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    Michael T. O'Donnell, PT, DPT; Stephen Reischl, PT, DPT, OCS

    Learning objectives

    Course Objectives:
    1. Discuss the inflammatory process, specifically the dual role macrophages play in the healing process.
    2. Distinguish between the difference between repair and regeneration and describe which process is the appropriate mechanism for specific body tissues.
    3. Describe mechanisms for injury, healing and adaptation of bone, articular cartilage, muscle, tendon, ligament and nerve.
    4. Describe appropriate time frames and extent of healing that occurs in bone ,articular cartilage, muscle, tendon, ligament and nerve.
    5. Discuss the impact of inflammation and co morbidities, such as diabetes and metabolic syndromes, have on tissue healing.
    6. Describe how the use of medications such as NSAIDs can influence tissue healing.
    7. Reflect on successful and unsuccessful outcomes resulting from evidence-based interventions.

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    2Assessment_LMS-682_Musculoskeletal Tissue Healing
    Type:E-Learning Course
    Credit Categories
    Domains:Musculoskeltal, O'Donnell, Reischl
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